ABSTRACT
To study a series of cases of Olfactory Neuroblastoma which is a rare neurogenic tumour. Design: A retrospective study of cases of Olfactory Neuroblastoma in a period of 11 years [From July 1985 to December 1995]. Subjects and Main outcome measures: 10 cases of Olfactory Neuroblastoma seen in last 11 years were assessed with clinical details, histological interpretation and result outcome of the regime of therapy. Age incidence ranged from 3 yrs. to 63 yrs. Males were 70%. 7 cases presented with unilateral nasal mass, nasal obstruction and epistaxis. Proptosis was seen in 2 cases while 3 had regional lymphadenopathy 50% cases were treated with initial surgical excision followed by cobalt therapy and cytotoxic drugs. Rest of the cases were managed by combination of cobalt therapy and chemotherapy. The patients with Olfactory Neuroblastoma must be continuously followed and evaluate for any regional and distant metastasis and also for local recurrence as it is very aggressive and highly malignant neoplasm. Overall survival rate is very poor